Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | 2514-30-9 | MFCD05856231 | 99.5% | 241.31 g/mol | C14H11NOS | 25 MG
PBIT is a research-grade small-molecule inhibitor of the Jumonji AT-rich interactive domain 1 (JARID1/KDM5) family of histone demethylases, showing activity against JARID1B (IC50 ≈ 3 μM). Supplied as a powder for laboratory use in epigenetics and chromatin biology research.
- Selective inhibitor of JARID1/KDM5 histone demethylases.
- Activity against JARID1B with IC50 ≈ 3 μM.
- High purity (99.5%).
- Powder form suitable for preparing solutions.
- Recommended storage: powder -20°C; in solvent -80°C for long-term storage.
- Includes datasheet with molecular formula and molecular weight.
Medchemexpress LLC Sirolimus (rapamycin) | 53123-88-9 | MFCD00867594 | 914.17 | C51H79NO13 | 50 MG
Rapamycin (sirolimus) GMP is a GMP-grade small-molecule mTOR inhibitor supplied as a white to off-white solid. It is intended for use as an auxiliary reagent in cell therapy manufacture and research, providing a GMP-sourced option for regulated workflows. Chemical identity is CAS 53123-88-9; formula C51H79NO13; molecular weight 914.17 g/mol.
- Potent, specific mTOR inhibitor used in research applications.
- GMP grade suitable for regulated cell therapy and biomanufacturing workflows.
- White to off-white solid; handle per product documentation and SDS.
- Chemical identity confirmed by CAS 53123-88-9.
- Available in multiple pack sizes, including 50 mg.
Medchemexpress LLC Sirolimus (rapamycin) | 53123-88-9 | MFCD00867594 | 914.17 g/mol | C51H79NO13 | 50 MG
Rapamycin (sirolimus) is a macrolide mTOR inhibitor supplied in a GMP-like grade for research and cell-therapy process applications. It is provided as a white to off-white solid intended for research use only and not for human therapeutic use.
- Acts as an mTOR inhibitor supporting autophagy and signaling pathway research.
- GMP-like grade suitable as an auxiliary reagent in cell therapy manufacture.
- Solid, white to off-white appearance for straightforward handling and storage.
- Molecular formula C51H79NO13 and molecular weight 914.17 g/mol for accurate formulation.
- CAS number 53123-88-9 enables unambiguous chemical identification.
Medchemexpress LLC Acetoxymethyl 2-(5-phenyl-1H-indol-3-yl)acetate | 2990123-10-7 | 99.0% | C19H17NO4 | 10MG
5-Ph-IAA-AM is an eggshell-permeable acetoxymethyl derivative of 5-Ph-IAA designed for use in auxin-inducible degron (AID2) systems. It provides enhanced protein degradation in laid C. elegans embryos, enabling temporally controlled depletion of target proteins to study embryogenesis and developmental processes.
- Eggshell-permeant analog facilitates delivery into laid embryos.
- Enhances protein degradation efficiency in AID2 systems.
- Compatible with OsTIR1(F74G)-mediated auxin-inducible degron assays.
- High purity supports reproducible experimental results.
- Powder is stable under recommended cold storage conditions.
![Medchemexpress LLC 5-chloro-N-[5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl]-2-hydroxybenzamide | 212135-62-1 | 96.0% | C22H15Cl3N2O2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261216.png-250.jpg)
Medchemexpress LLC 5-chloro-N-[5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl]-2-hydroxybenzamide | 212135-62-1 | 96.0% | C22H15Cl3N2O2 | 10MG
ZT-1a is a small-molecule, non-ATP-competitive inhibitor of STE20/SPS1-related proline-alanine-rich kinase (SPAK/STK39). It has been reported to inhibit SPAK enzymatic activity with mid-micromolar IC50 values and is used as a biochemical probe to study SPAK-dependent regulation of ion transporters.
- Non-ATP-competitive inhibition of SPAK
- Reported IC50 values: 44.3 μM (0.01 mM ATP), 35.0 μM (0.1 mM ATP), 46.7 μM (1 mM ATP)
- Molecular formula: C22H15Cl3N2O2
- Molecular weight: 445.73 g·mol⁻¹
- Useful as a biochemical probe for studying SPAK-dependent signaling
- Available in small research quantities for in vitro studies
![Biolegend Purified anti-human IFN-β [W20086B]; Isotype: Mouse IgG2b, κ; Reactivity: Human; Apps: Direct ELISA; Size: 100 μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502723714.png-250.jpg)
Biolegend Purified anti-human IFN-β [W20086B]; Isotype: Mouse IgG2b, κ; Reactivity: Human; Apps: Direct ELISA; Size: 100 μg
Purified anti-human IFN-β [W20086B]; Isotype: Mouse IgG2b, κ; Reactivity: Human; Apps: Direct ELISA; Size: 100 μg
Selleck Chemical LLC Lubiprostone S1675-2mg
Lubiprostone (RU 0211 SPI-0211) is an activator of ClC-2 chloride channels used in the management of idiopathic chronic constipation
Selleck Chemical LLC Hydrocortisone S1696-200mg
Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland
Selleck Chemical LLC Cyclophosphamide Monohydrate S2057-200mg
Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent it attaches the alkyl group to the guanine base of DNA shown to crosslink DNA causing strand breakage and inducing mutations Cyclophosphamide (NSC-26271) Monohydrate can be used to induce animal models of Anemia
Selleck Chemical LLC Tanespimycin (17-AAG) S1141-1g
Tanespimycin (17-AAG CP127374 NSC-330507 KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells Tanespimycin (17-AAG) induces apoptosis necrosis autophagy and mitophagy Phase 3
Cell Applications Inc Human Endothelial Cell Growth Supplement wo Hydrocortisone
Human Endothelial Cell Growth Supplement wo Hydrocortisone
Cell Applications Inc Human Microvascular Endothelial Cell Growth Supplement
Human Microvascular Endothelial Cell Growth Supplement
Cell Applications Inc Human Chondrocyte Differentiation Media wo Phenol Red
Human Chondrocyte Differentiation Media wo Phenol Red